SCHEMBL30002378

SCHEMBL30002378

CC(C)C(=O)Nc1nc(OC(=O)N(c2ccccc2)c2ccccc2)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 6/20 0.52
ADORA3 P0DMS8 4/20 0.52
ADORA1 P30542 3/20 0.52
ADORA2B P29275 2/20 0.50
CYP1A2 P05177 2/20 0.49
THPO P40225 1/20 0.49
MEN1 O00255 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49
BLM P54132 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25496787 0.91 ADORA2A (0.44) ADORA2AADORA3ADORA1ADORA2BCYP1A2
SCHEMBL8768130 0.90 ADORA2A (0.56) ADORA2AADORA3ADORA1ADORA2BCYP1A2
SCHEMBL1066408 0.90 ADORA2A (0.53) ADORA2AADORA3ADORA1ADORA2BCYP1A2
SCHEMBL14665042 0.90 ADORA2A (0.53) ADORA2AADORA3ADORA1ADORA2BCYP1A2
SCHEMBL14665046 0.90 ADORA2A (0.53) ADORA2AADORA3ADORA1ADORA2BCYP1A2
SCHEMBL8972045 0.86 KDM4E (0.44) ADORA3ADORA1
SCHEMBL30002219 0.86 TYMP (0.56) ADORA1
SCHEMBL25504326 0.84 HINT1 (0.38) ADORA2AADORA3ADORA1ADORA2B
SCHEMBL25496785 0.81 ADORA2A (0.37) ADORA2AADORA3ADORA1ADORA2BCYP1A2
SCHEMBL24703675 0.81 ADORA3 (0.42) ADORA2AADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262859-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME UNIV TOKYO SCIENCE FOUND (JP) 2024-08-08 US disclosed
EP-4349846-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2024-04-10 EP disclosed
CN-117412983-A Chimeric nucleic acid oligomer comprising phosphorothioate and borazine phosphate, and method for producing same 学校法人东京理科大学 2024-01-16 CN disclosed
WO-2022255469-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME 学校法人東京理科大学 2022-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262859-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME RNGTT, NSUN2, MTAP ADORA2A 173/4885ADORA3 69/4885ADORA1 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.