Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972094 | 0.88 | TYMP (0.38) | KDM4EADORA3ADORA1PNPLMNA | |
| SCHEMBL18844546 | 0.88 | KDM4E (0.48) | KDM4EADORA3ADORA1 | |
| SCHEMBL30002378 | 0.86 | ADORA2A (0.52) | ADORA3ADORA1 | |
| SCHEMBL29776895 | 0.86 | KDM4E (0.46) | KDM4EADORA3ADORA1 | |
| SCHEMBL17943450 | 0.86 | KDM4E (0.46) | KDM4EADORA3ADORA1 | |
| SCHEMBL17676618 | 0.86 | KDM4E (0.46) | KDM4EADORA3ADORA1 | |
| SCHEMBL18462900 | 0.86 | KDM4E (0.46) | KDM4EADORA3ADORA1 | |
| SCHEMBL14985923 | 0.86 | KDM4E (0.46) | KDM4EADORA3ADORA1 | |
| SCHEMBL6899599 | 0.85 | ADORA3 (0.40) | ADORA3ADORA1PNPLMNATP53 | |
| SCHEMBL25496787 | 0.82 | ADORA2A (0.44) | ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541307-A | Backbone modified oligonucleotide analogs and solid phase synthesis thereof | ISIS PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |