SCHEMBL8972170

SCHEMBL8972170

C=CCC(c1ccc(C(C)(CC=C)N2C(=O)C3C4C=CC(C4)C3C2=O)cc1)N1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 5/20 0.32
HTT P42858 1/20 0.32
ALDH1A1 P00352 5/20 0.32
TSHR P16473 3/20 0.32
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970926 0.79 ALDH1A1 (0.46) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8972029 0.78 ALDH1A1 (0.47) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8971770 0.70 ALDH1A1 (0.39) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8971289 0.69 MEN1 (0.51) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8970956 0.69 MEN1 (0.46) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8854362 0.66 MEN1 (0.44) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8971865 0.65 MEN1 (0.42) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8971905 0.65 KMT2A (0.47) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8854422 0.64 MEN1 (0.55) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL8971286 0.64 ALDH1A1 (0.45) MEN1KMT2ALMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521260-A ALKENYLNADIMIDE, VINYL COMPOUND, PHENOLIC RESIN MARUZEN PETROCHEMICAL CO., LTD. (JP) 1996-05-28 US disclosed