Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | Q9HBH1 | 1/20 | 0.42 | |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21485282 | 1.00 | BIRC2 (0.53) | BIRC2ALDH1A1FOLH1TAS1R3TAS1R1 | |
| SCHEMBL23133171 | 1.00 | BIRC2 (0.53) | BIRC2ALDH1A1FOLH1TAS1R3TAS1R1 | |
| SCHEMBL21387168 | 0.87 | ALDH1A1 (0.50) | BIRC2ALDH1A1MMP3MMP9FURIN | |
| SCHEMBL27097853 | 0.86 | BIRC2 (0.57) | BIRC2ALDH1A1FOLH1TAS1R3TAS1R1 | |
| SCHEMBL24178319 | 0.86 | BIRC2 (0.57) | BIRC2ALDH1A1FOLH1TAS1R3TAS1R1 | |
| SCHEMBL11042902 | 0.86 | CA1 (0.53) | BIRC2TAS1R3TAS1R1PDFCA1 | |
| SCHEMBL27883776 | 0.86 | CA1 (0.53) | BIRC2TAS1R3TAS1R1PDFCA1 | |
| SCHEMBL11128090 | 0.86 | CA1 (0.53) | BIRC2TAS1R3TAS1R1PDFCA1 | |
| SCHEMBL7332515 | 0.86 | BIRC2 (0.57) | BIRC2FOLH1TAS1R3TAS1R1MME | |
| SCHEMBL3426049 | 0.85 | ALDH1A1 (0.62) | ALDH1A1FOLH1MMP3MMP9MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |