Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972166 | 0.91 | S1PR1 (0.31) | SPHK2S1PR1 | |
| SCHEMBL8972172 | 0.86 | SPHK2 (0.32) | SPHK2S1PR1PLA2G2D | |
| SCHEMBL8972478 | 0.86 | SPHK2 (0.32) | SPHK2S1PR1PLA2G2D | |
| SCHEMBL8972099 | 0.85 | PPARD (0.37) | — | |
| SCHEMBL8972296 | 0.84 | — | — | |
| SCHEMBL8972256 | 0.84 | — | — | |
| SCHEMBL8970766 | 0.83 | CNR2 (0.32) | — | |
| SCHEMBL8971952 | 0.82 | PLA2G2D (0.32) | S1PR1PLA2G2D | |
| SCHEMBL8970559 | 0.81 | PTPN11 (0.32) | S1PR1 | |
| SCHEMBL8972339 | 0.81 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |