Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.37 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 7/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972166 | 0.85 | S1PR1 (0.31) | — | |
| SCHEMBL8972175 | 0.85 | SPHK2 (0.32) | — | |
| SCHEMBL8972100 | 0.84 | RORC (0.34) | PPARDRORCRORANR1H4 | |
| SCHEMBL8972420 | 0.83 | PPARD (0.36) | PPARDRORCRORANR1H4PPARA | |
| SCHEMBL8971099 | 0.82 | RARB (0.33) | PPARD | |
| SCHEMBL8948466 | 0.82 | FPR2 (0.33) | PPARDALOX5APFEN1 | |
| SCHEMBL8971848 | 0.81 | GRM2 (0.35) | PPARD | |
| SCHEMBL8948506 | 0.81 | FPR2 (0.33) | PPARD | |
| SCHEMBL8971484 | 0.81 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL8970738 | 0.80 | S1PR1 (0.34) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |