Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13127115 | 0.79 | AGTR1 (0.44) | AGTR1LTB4R2 | |
| SCHEMBL8971440 | 0.76 | — | — | |
| SCHEMBL9671914 | 0.75 | AGTR1 (0.58) | AGTR1LTB4R2 | |
| SCHEMBL388099 | 0.73 | AGTR1 (0.56) | AGTR1LTB4R2 | |
| SCHEMBL9081604 | 0.72 | AGTR1 (0.46) | AGTR1LTB4R2 | |
| SCHEMBL8972530 | 0.72 | AGTR1 (0.56) | AGTR1 | |
| SCHEMBL9313919 | 0.72 | AGTR1 (0.40) | AGTR1LTB4R2 | |
| SCHEMBL8972259 | 0.72 | AGTR1 (0.56) | AGTR1 | |
| SCHEMBL9082860 | 0.71 | AGTR1 (0.45) | AGTR1LTB4R2 | |
| SCHEMBL9084369 | 0.71 | AGTR1 (0.45) | AGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506238-A | HYPOTENSIVE AGENT | EISAI CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0628557-A1 | Biphenylmethane derivatives, the use of them and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5298518-A | Biphenylmethane derivative and pharmacological use | EISAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |