Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591645 | 1.00 | PRKCA (0.40) | PRKCAPRKCETLR4NLRP3MAPT | |
| SCHEMBL8972434 | 0.94 | PRKCA (0.41) | PRKCAPRKCETLR4MAPTCYP3A4 | |
| SCHEMBL8972911 | 0.92 | MAPT (0.47) | PRKCAPRKCETLR4MAPTALDH1A1 | |
| SCHEMBL9593341 | 0.89 | TLR4 (0.38) | PRKCAPRKCETLR4PRKD3PRKCG | |
| SCHEMBL8972916 | 0.89 | TLR4 (0.38) | PRKCAPRKCETLR4PRKD3PRKCG | |
| SCHEMBL9701141 | 0.89 | TLR4 (0.38) | PRKCAPRKCETLR4PRKD3PRKCG | |
| SCHEMBL9592142 | 0.83 | PTPN1 (0.38) | MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL9701017 | 0.83 | PTPN1 (0.38) | MAPTALDH1A1CYP3A4TSHR | |
| SCHEMBL11762251 | 0.82 | TLR4 (0.41) | TLR4NLRP3DGKA | |
| SCHEMBL1471700 | 0.81 | DGKA (0.53) | NLRP3MAPTALDH1A1TSHRDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484063-B1 | Process for preparing optically active epoxy alcohols | NITTO DENKO CORP (JP) | 1996-03-06 | — | — | EP | disclosed |
| US-5213975-A | METHODS OF PREPARING OPTICALLY ACTIVE EPOXY ALCOHOL | NITTO DENKO CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0484063-A2 | Process for preparing optically active epoxy alcohols | Nitto Denko Co. Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |