Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295051 | 0.80 | MAOA (0.43) | MAOAMAOBGAANPSR1 | |
| SCHEMBL7217002 | 0.78 | MAOA (0.45) | MAOAMAOBGAANPSR1 | |
| SCHEMBL10824456 | 0.78 | GABRA1 (0.33) | GAANPSR1CYP1A2CYP3A4MAPT | |
| SCHEMBL295013 | 0.77 | MAOA (0.41) | MAOAMAOBGAANPSR1 | |
| SCHEMBL9935109 | 0.77 | MAOA (0.43) | MAOAMAOBGAANPSR1 | |
| SCHEMBL3626527 | 0.77 | MAOA (0.43) | MAOAMAOBGAANPSR1 | |
| SCHEMBL4206535 | 0.77 | MAOA (0.43) | MAOAMAOBGAANPSR1 | |
| SCHEMBL3804887 | 0.76 | CYP1A2 (0.38) | CYP1A2CYP3A4MAPT | |
| SCHEMBL11809072 | 0.75 | GABRA1 (0.38) | MAOAMAOBGAAADRA1DADRA1A | |
| SCHEMBL294713 | 0.75 | MAOA (0.38) | MAOAMAOBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054848-C | New benzopyran derivatives, their process of preparation and pharmaceutical compositions which contain them | ADIR (FR) | 2000-07-26 | — | — | CN | disclosed |
| CN-1132202-A | New benzopyran derivatives, their process of preparation and pharmaceutical compositions which contain them | ADIR (FR) | 1996-10-02 | — | — | CN | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |
| US-5447943-A | Smooth muscle relaxants or bronchodilators | SYNTEX (U.S.A.) INC. (US) | 1995-09-05 | — | — | US | disclosed |
| US-5250547-A | Potassium channel activators; 5-lipoxygenase inhibitors; muscle relaxants; bronchodilators | SYNTEX (U.S.A.) INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0529654-A1 | Benzopyran derivatives as potassium channel activators and 5-lipoxygenase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1993-03-03 | — | — | EP | disclosed |