SCHEMBL8972589

SCHEMBL8972589

CCN(O)c1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188020 0.71 ALDH1A1 (0.39) LMNA
SCHEMBL11796805 0.68 TSHR (0.37)
SCHEMBL79695 0.68 CCNB2 (0.31) KDM4E
SCHEMBL81829 0.67 KDM4E (0.32) KDM4ELMNAPKM
SCHEMBL8980533 0.67
SCHEMBL6723865 0.67 MAPT (0.39) KDM4ELMNA
SCHEMBL10623884 0.67
SCHEMBL8605492 0.67 SLC29A1 (0.47) KDM4ELMNA
SCHEMBL8384091 0.66 KDM4E (0.33) KDM4ELMNAPKM
SCHEMBL3822649 0.64 KDM4E (0.37) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663690-B2 UV-curable silicone release compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-05-30 US disclosed
EP-2917295-A1 UV-CURABLE SILICONE RELEASE COMPOSITIONS 3M Innovative Properties Company (US) 2015-09-16 EP disclosed
EP-2917298-A1 UV-CURABLE SILICONE ADHESIVE COMPOSITIONS 3M Innovative Properties Company (US) 2015-09-16 EP disclosed
US-20150252235-A1 UV-CURABLE SILICONE ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-09-10 US disclosed
US-20150247078-A1 UV-CURABLE SILICONE RELEASE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2015-09-03 US disclosed
WO-2014074372-A1 UV-CURABLE SILICONE RELEASE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-15 WO disclosed
WO-2014074336-A1 UV-CURABLE SILICONE ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-15 WO disclosed
EP-0361682-B1 Halomethyl-1,3,5-triazines containing a photoinitiator moiety MINNESOTA MINING & MFG (US) 1996-03-27 EP disclosed
US-5153323-A Halomethyl-1,3,5-triazines containing a photoinitiator moiety MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-06 US disclosed
EP-0361682-A1 Halomethyl-1,3,5-triazines containing a photoinitiator moiety MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-04 EP disclosed