Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972681 | 1.00 | MAPK1 (0.61) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL25198153 | 0.88 | MAPK1 (0.65) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL29477178 | 0.81 | MAPT (0.56) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL8458428 | 0.81 | MAPT (0.56) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL8458429 | 0.81 | MAPT (0.56) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL10070208 | 0.80 | KDM4E (0.68) | MAPK1MAPTSMN1; SMN2KDM4ECXCL12 | |
| SCHEMBL2997293 | 0.80 | XDH (0.74) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL25201250 | 0.80 | XDH (0.74) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL2997295 | 0.80 | XDH (0.74) | MAPK1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL25195971 | 0.80 | XDH (0.74) | MAPK1MAPTTP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619116-A2 | Use of synthetic retinoids for osteopathy | HOECHST JAPAN LIMITED (JP) | 1994-10-12 | — | — | EP | claimed |
| US-5525618-A | ENHANCING OSTEOGENESIS, PREVENTING OSTEOPOROSIS | HOECHST JAPAN LIMITED (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0619116-A2 | Use of synthetic retinoids for osteopathy | HOECHST JAPAN LIMITED (JP) | 1994-10-12 | — | — | EP | disclosed |