Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.55 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.49 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729712 | 0.83 | PLA2G4A (0.70) | PLA2G4ALPAR3 | |
| Phosphorylethanolamine SCHEMBL8973011 | 0.83 | LPAR3 (0.56) | PLA2G4ALPAR3 | |
| Phosphoric Acid SCHEMBL8972909 | 0.82 | PLA2G2C (0.59) | PLA2G4ALPAR3 | |
| SCHEMBL3449056 | 0.81 | LPAR3 (0.67) | PLA2G4ALPAR3 | |
| Dexfosfoserine SCHEMBL8973494 | 0.81 | S1PR1 (0.47) | P2RY10GPR174S1PR2S1PR1S1PR3 | |
| SCHEMBL24767613 | 0.79 | PLA2G2C (0.66) | NOD1 | |
| SCHEMBL22911002 | 0.79 | PLA2G2C (0.66) | NOD1 | |
| SCHEMBL21428136 | 0.79 | PLA2G2C (0.66) | NOD1 | |
| SCHEMBL21428309 | 0.79 | PLA2G2C (0.66) | NOD1 | |
| SCHEMBL14627191 | 0.79 | PLA2G2C (0.66) | NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | claimed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | claimed |
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | disclosed |