SCHEMBL8972715

SCHEMBL8972715

COC(OC)C(CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTSK P43235 12/20 0.69
CTSL P07711 6/20 0.65
CTSS P25774 3/20 0.65
CTSB P07858 3/20 0.65
PSMB1 P20618 1/20 0.62
CAPN1 P07384 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3333284 0.90 CTSK (0.60) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL8972325 0.89 CTSK (0.63) CTSKCTSLCTSSCTSBPSMB1
SCHEMBL7163409 0.85 CTSK (0.75) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL26292318 0.85 CTSK (0.75) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL4575868 0.85 CTSK (0.75) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL1841693 0.85 CTSK (0.70) CTSKCTSLCTSSCTSBPSMB1
SCHEMBL8972198 0.84 CTSK (0.65) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL8823936 0.84 CAPN1 (0.78) CTSKCTSLCTSSCTSBCAPN1
SCHEMBL6828336 0.84 CTSK (0.66) CTSKCTSLCTSSCTSBPSMB1
SCHEMBL25406813 0.84 CTSK (0.77) CTSKCTSLCTSSCTSBCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543310-B1 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LTD (JP) 1996-03-27 EP disclosed
US-5395824-A Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1995-03-07 US disclosed
EP-0543310-A2 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1993-05-26 EP disclosed