Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.66 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 5/20 | 0.62 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828151 | 0.87 | CTSK (0.61) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL6444976 | 0.84 | CTSK (0.72) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL8972715 | 0.84 | CTSK (0.69) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL6828785 | 0.83 | CTSK (0.59) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL11302590 | 0.83 | CTSK (0.74) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL1841693 | 0.83 | CTSK (0.70) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL7344647 | 0.83 | CTSK (0.64) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL7344663 | 0.83 | CTSK (0.64) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL8951282 | 0.82 | CAPN1 (0.66) | CTSKPSMB1CTSLCTSBCTSS | |
| SCHEMBL25406813 | 0.82 | CTSK (0.77) | CTSKCTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389624-A1 | Phosphorous-containing cysteine and serine protease inhibitors | CEPHALON, INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| US-5639732-A | FOR TREATING NERVOUS SYSTEM DISORDERS OR AS ANTIINFLAMMATORY AGENT | CEPHALON, INC. (US) | 1997-06-17 | — | — | US | disclosed |