Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
| ▸ | PIKFYVE | Q9Y2I7 | 3/20 | 0.33 |
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972368 | 0.92 | AKR1C2 (0.43) | AKR1C2HAO1MTNR1ACYP1A2CYP3A4 | |
| SCHEMBL8972920 | 0.90 | AKR1C2 (0.43) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8972923 | 0.90 | AKR1C2 (0.42) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8972800 | 0.90 | AKR1C2 (0.42) | AKR1C2HAO1MTNR1ACYP1A2CYP3A4 | |
| SCHEMBL8972907 | 0.86 | AKR1C2 (0.48) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8973400 | 0.85 | AKR1C2 (0.45) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8972398 | 0.83 | AKR1C2 (0.43) | AKR1C2HAO1MTNR1ACYP1A2CYP3A4 | |
| SCHEMBL8961310 | 0.83 | AKR1C2 (0.43) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8626809 | 0.82 | AKR1C2 (0.44) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4159791 | 0.82 | AKR1C2 (0.44) | AKR1C2MTNR1ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | disclosed |
| US-5451696-A | Parasiticide intermediate | ROUSSEL-UCLAF (FR) | 1995-09-19 | — | — | US | disclosed |
| US-5380883-A | Insecticide, nematocide, miticide | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | disclosed |