Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972907 | 0.87 | AKR1C2 (0.48) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8973400 | 0.86 | AKR1C2 (0.45) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8972398 | 0.84 | AKR1C2 (0.43) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8972368 | 0.84 | AKR1C2 (0.43) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4159791 | 0.83 | AKR1C2 (0.44) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8626809 | 0.83 | AKR1C2 (0.44) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8972774 | 0.83 | AKR1C2 (0.42) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8972978 | 0.82 | AKR1C2 (0.43) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8972923 | 0.82 | AKR1C2 (0.42) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8972800 | 0.82 | AKR1C2 (0.42) | AKR1C2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | claimed |
| EP-0693877-A1 | USE OF 7-ETHYNYL $g(a)-(METHOXYMETHYLENE) 1-NAPHTHALENE ACETIC ACID DERIVATIVES FOR PREPARING FUNGICIDAL COMPOSITIONS | ROUSSEL UCLAF (FR) | 1996-01-31 | — | — | EP | claimed |
| US-5380883-A | Insecticide, nematocide, miticide | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | claimed |
| WO-1994023576-A1 | USE OF 7-ETHYNYL α-(METHOXYMETHYLENE) 1-NAPHTHALENE ACETIC ACID DERIVATIVES FOR PREPARING FUNGICIDAL COMPOSITIONS | ROUSSEL UCLAF (FR) | 1994-10-27 | — | — | WO | claimed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | claimed |
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | disclosed |
| US-5451696-A | Parasiticide intermediate | ROUSSEL-UCLAF (FR) | 1995-09-19 | — | — | US | disclosed |
| US-5380883-A | Insecticide, nematocide, miticide | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | disclosed |
| EP-0538097-A1 | Naphthalene-1-acetic-acid derivatives, their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-04-21 | — | — | EP | disclosed |