Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566359 | 0.89 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL8561748 | 0.88 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8971897 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8971480 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8971607 | 0.85 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8972044 | 0.85 | AGTR1 (0.65) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL9053252 | 0.84 | AGTR1 (0.64) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL9847776 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL8972215 | 0.83 | AGTR1 (0.60) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL8972320 | 0.83 | AGTR1 (0.60) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506238-A | HYPOTENSIVE AGENT | EISAI CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0628557-A1 | Biphenylmethane derivatives, the use of them and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328911-A | Cardiovascular disorders, hypotensive agents and congestive heart failure | EISAI CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |