Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972914 | 1.00 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1FASN | |
| SCHEMBL8972921 | 1.00 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1FASN | |
| SCHEMBL8972910 | 1.00 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1FASN | |
| SCHEMBL8972905 | 1.00 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1FASN | |
| SCHEMBL31343 | 0.92 | KDM1A (0.43) | KDM1AESR2TRPV4CHEK1FASN | |
| SCHEMBL14274413 | 0.92 | KDM1A (0.43) | KDM1AESR2TRPV4CHEK1FASN | |
| SCHEMBL10616074 | 0.88 | TRPV4 (0.38) | KDM1ATRPV4CHEK1FASNCYP11B1 | |
| SCHEMBL10616060 | 0.88 | TRPV4 (0.38) | KDM1ATRPV4CHEK1FASNCYP11B1 | |
| SCHEMBL10616067 | 0.88 | TRPV4 (0.38) | KDM1ATRPV4CHEK1FASNCYP11B1 | |
| SCHEMBL10616055 | 0.88 | TRPV4 (0.38) | KDM1ATRPV4CHEK1FASNCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588291-B1 | 2-Fluorobenzonitrile derivative | CHISSO CORP (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5370822-A | Liquid crystals | CHISSO CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0588291-A1 | 2-Fluorobenzonitrile derivative | Chisso Corporation (JP) | 1994-03-23 | — | — | EP | disclosed |