Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973166 | 1.00 | OPRM1 (0.39) | OPRM1GPR84SPHK1LMNADNM1 | |
| SCHEMBL8973592 | 1.00 | OPRM1 (0.39) | OPRM1GPR84SPHK1LMNADNM1 | |
| SCHEMBL8973370 | 1.00 | OPRM1 (0.39) | OPRM1GPR84SPHK1LMNADNM1 | |
| SCHEMBL6907025 | 0.80 | GPR84 (0.35) | OPRM1GPR84SPHK1LMNADNM1 | |
| SCHEMBL5482895 | 0.78 | GPR84 (0.42) | GPR84SPHK1LMNA | |
| SCHEMBL5489484 | 0.78 | GPR84 (0.42) | GPR84SPHK1LMNA | |
| SCHEMBL6910830 | 0.78 | OPRM1 (0.35) | OPRM1GPR84SPHK1 | |
| SCHEMBL3641987 | 0.77 | OPRM1 (0.37) | OPRM1GPR84LMNADNM1 | |
| SCHEMBL6684349 | 0.74 | CSNK1E (0.42) | OPRM1GPR84SPHK1TSHR | |
| SCHEMBL20241831 | 0.74 | OPRM1 (0.34) | OPRM1LMNADNM1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381149-B1 | Optically active compound, liquid crystal composition and liquid crystal device comprising same | SHARP KK (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5264152-A | Ferroelectric | SHARP KABUSHIKI KAISHA (JP) | 1993-11-23 | — | — | US | disclosed |