Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331538 | 0.78 | BCHE (0.46) | BCHENPSR1ACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL9332148 | 0.77 | LMNA (0.45) | BCHENPSR1ACHEALDH1A1 | |
| SCHEMBL9334774 | 0.76 | BCHE (0.41) | BCHENPSR1ACHEMAPTALDH1A1 | |
| SCHEMBL9501784 | 0.74 | BCHE (0.47) | BCHEALDH1A1 | |
| SCHEMBL144450 | 0.74 | KDM1A (0.50) | BCHEKDM1AACHEMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9784864 | 0.74 | BCHE (0.47) | BCHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL9332079 | 0.73 | HRH1 (0.43) | BCHENPSR1MAPTUSP2ALDH1A1 | |
| SCHEMBL9332058 | 0.73 | HDAC3 (0.45) | BCHENPSR1MAPTUSP2ALDH1A1 | |
| SCHEMBL9331502 | 0.73 | DRD3 (0.44) | KDM1AACHEMAPTUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9331483 | 0.72 | DRD3 (0.44) | BCHENPSR1KDM1AACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633780-B1 | USE OF PHENOTHIAZINE DERIVATIVES FOR TREATING ISCHAEMIA AND/OR HYPOXIA | RHONE POULENC RORER SA (FR) | 1996-06-05 | — | — | EP | claimed |
| US-5502049-A | AMINOALKYL AND AMIDE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1996-03-26 | — | — | US | claimed |