Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972054 | 0.97 | CETP (0.40) | TLR2CETPPLA2G2AL3MBTL1LPAR1 | |
| SCHEMBL8732993 | 0.87 | CETP (0.40) | CETPS1PR4S1PR1S1PR3S1PR2 | |
| SCHEMBL8729241 | 0.87 | CETP (0.40) | CETPS1PR4S1PR1S1PR3S1PR2 | |
| SCHEMBL8733002 | 0.87 | CETP (0.40) | CETPS1PR4S1PR1S1PR3S1PR2 | |
| SCHEMBL8972694 | 0.85 | CETP (0.50) | CETPLPAR1LPAR3 | |
| SCHEMBL8973335 | 0.85 | CETP (0.50) | CETPLPAR1LPAR3 | |
| SCHEMBL8972562 | 0.85 | CETP (0.50) | CETPLPAR1LPAR3 | |
| SCHEMBL8728138 | 0.84 | CETP (0.41) | CETPS1PR4S1PR1S1PR3S1PR2 | |
| SCHEMBL8733228 | 0.83 | CETP (0.52) | CETPS1PR4S1PR1S1PR3S1PR2 | |
| SCHEMBL8733051 | 0.83 | CETP (0.43) | CETPLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994028004-A1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | LABORATORIOS MENARINI S.A. (ES) | 1994-12-08 | — | — | WO | disclosed |