Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972694 | 0.87 | CETP (0.50) | CETP | |
| SCHEMBL8973335 | 0.87 | CETP (0.50) | CETP | |
| SCHEMBL8972562 | 0.87 | CETP (0.50) | CETP | |
| SCHEMBL8730243 | 0.85 | PLA2G2A (0.47) | CETP | |
| SCHEMBL8733002 | 0.84 | CETP (0.40) | CETPS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8729241 | 0.84 | CETP (0.40) | CETPS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8732993 | 0.84 | CETP (0.40) | CETPS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8973086 | 0.83 | TLR2 (0.40) | CETPS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8728138 | 0.81 | CETP (0.41) | CETPS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8972402 | 0.81 | PLA2G2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701561-B1 | DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 | MENARINI LAB (ES) | 1998-08-19 | — | — | EP | claimed |