Dimethylamine

Dimethylamine

SCHEMBL8973174

CC(=O)NC1(Nc2ccccc2)C(=O)N(c2ccccc2)N=C1c1ccccc1.CNC

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
GAA P10253 4/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
POLB P06746 2/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
LMNA P02545 3/20 0.33
MAPK1 P28482 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RIPK1 Q13546 1/20 0.32
HTT P42858 2/20 0.32
CES2 O00748 1/20 0.32
ATM Q13315 1/20 0.32
PKM P14618 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL7762459 0.91 MEN1 (0.36) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL7759212 0.88 MEN1 (0.37) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL7756113 0.87 KDM4E (0.38) MEN1KMT2AGAAALDH1A1SMN1; SMN2
Dimethylamine SCHEMBL7759251 0.86 SMN1; SMN2 (0.44) MEN1KMT2AGAAALDH1A1MAPT
Diethylamine SCHEMBL7759271 0.86 GABRA2 (0.35) MEN1KMT2AGAAALDH1A1MAPT
Diethylamine SCHEMBL7762446 0.86 KMT2A (0.34) MEN1KMT2AMAPTSMN1; SMN2RIPK1
SCHEMBL7762454 0.86 NOX1 (0.43) MEN1KMT2AGAAALDH1A1MAPT
Dimethylamine SCHEMBL7762410 0.84 MAPT (0.36) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL7756111 0.82 CNR2 (0.38) MEN1KMT2AGAAALDH1A1MAPT
Dimethylamine SCHEMBL7760667 0.81 MEN1 (0.38) MEN1KMT2AGAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed