SCHEMBL8973274

SCHEMBL8973274

CCCCCc1nc(-c2ccccc2)[nH]c1C

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 1/20 0.52
DHFR P00374 1/20 0.47
NPY5R Q15761 1/20 0.47
PIN1 Q13526 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
GCGR P47871 1/20 0.46
GPR84 Q9NQS5 1/20 0.44
HSD11B1 P28845 1/20 0.43
HPGDS O60760 1/20 0.43
XDH P47989 1/20 0.41
MAPT P10636 1/20 0.41
ADORA2B P29275 1/20 0.41
PDE5A O76074 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6616423 0.95 SMPD3 (0.57) SMPD3DHFRNPY5RPIN1DRD2
SCHEMBL28412520 0.82 PIN1 (0.53) DHFRNPY5RPIN1DRD2DRD4
SCHEMBL6214064 0.81 PIN1 (0.49) SMPD3NPY5RPIN1DRD2DRD4
SCHEMBL1435698 0.81 PIN1 (0.49) SMPD3NPY5RPIN1DRD2DRD4
SCHEMBL6214539 0.81 PIN1 (0.53) SMPD3NPY5RPIN1DRD2DRD4
Hydrochloric Acid SCHEMBL6219343 0.79 PIN1 (0.47) SMPD3NPY5RPIN1DRD2DRD4
SCHEMBL31531720 0.77 XDH (0.43) DHFRGCGRGPR84HSD11B1XDH
SCHEMBL1099825 0.77 PIN1 (0.56) SMPD3NPY5RPIN1DRD2DRD4
SCHEMBL1436137 0.77 PIN1 (0.51) SMPD3NPY5RPIN1DRD2DRD4
SCHEMBL6618223 0.76 GCGR (0.44) SMPD3DHFRPIN1GCGRXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5560785-A TREATING SURFACE WITH SOLUTION OF IMIDAZOLE COMPOUND, COPPER COMPOUND, ZINC COMPOUND, STABILIZERS SHIKOKU CHEMICALS CORPORATION (JP) 1996-10-01 US disclosed
US-5498301-A ON A PRINTED WIRING BOARD, HEAT RESISTANT, MOISTURE RESISTANT, A 2-ARYLIMIDAZOLE, CARBOXYLIC ACID, AMMONIA, WATER SHIKOKU CHEMICALS CORPORATION (JP) 1996-03-12 US disclosed
EP-0627499-A1 Agent for treating surfaces of copper and copper alloys SHIKOKU CHEMICALS CORPORATION (JP) 1994-12-07 EP disclosed