Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18505011 | 0.81 | LMNA (0.50) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL748982 | 0.81 | LMNA (0.50) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL765677 | 0.81 | LMNA (0.50) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL23961372 | 0.79 | IDO1 (0.48) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8221027 | 0.79 | IDO1 (0.48) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9480536 | 0.78 | IDO1 (0.52) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27806416 | 0.78 | ADRB2 (0.55) | CYP2D6SLC6A2SLC6A4KCNH2TSHR | |
| SCHEMBL4450092 | 0.77 | IDO1 (0.47) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL6014412 | 0.77 | TAAR1 (0.56) | HPGDHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5873472 | 0.77 | IDO1 (0.50) | HPGDHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985402-A | FRAGRANCE FOR DETERGENTS, COSMETICS, BLEACHES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-01-15 | — | — | US | claimed |
| EP-0440362-B1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INT FLAVORS & FRAGRANCES INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0440362-A1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| EP-0440362-A1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-08-07 | — | — | EP | disclosed |
| EP-0440362-A1 | 2,2-Dimethyl-1-nitrilo or 2,2-dimethyl-1-hydroxylamino-3-(alkyl phenyl)substituted propanes or 2-methyl-1-nitrilo-or 2-methyl-1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-08-07 | — | — | EP | disclosed |