Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25583638 | 0.78 | CYP19A1 (0.50) | PARP10EPHX2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3910348 | 0.78 | CYP19A1 (0.50) | PARP10EPHX2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL25583651 | 0.78 | CYP19A1 (0.50) | PARP10EPHX2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL943014 | 0.77 | PARP10 (0.46) | PARP10HPGDEPHX2ALDH1A1TSHR | |
| SCHEMBL18058688 | 0.77 | SMN1; SMN2 (0.54) | PARP10HPGDEPHX2ALDH1A1TSHR | |
| SCHEMBL2242868 | 0.76 | PARP10 (0.55) | PARP10HPGDEPHX2ALDH1A1TSHR | |
| SCHEMBL8973048 | 0.76 | MAPT (0.50) | PARP10EPHX2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3457580 | 0.75 | PARP10 (0.47) | PARP10HPGDEPHX2ALDH1A1TSHR | |
| SCHEMBL20443245 | 0.73 | MAOB (0.47) | PARP10HPGDEPHX2ALDH1A1TSHR | |
| SCHEMBL510644 | 0.72 | FBP1 (0.55) | HPGDALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335274-B1 | Formation of nitrophenyl ethers from polyols and nitroanisoles | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | disclosed |
| US-4960950-A | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |