Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791086 | 0.93 | POLB (0.32) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8791090 | 0.85 | POLB (0.31) | POLBMEN1KMT2AITGB1ITGA2 | |
| SCHEMBL8791931 | 0.83 | ALDH1A1 (0.36) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8791819 | 0.79 | KDM4E (0.38) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8790908 | 0.73 | DPP4 (0.38) | ALDH1A1LMNA | |
| SCHEMBL8789847 | 0.71 | DAO (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8790916 | 0.71 | KMT2A (0.38) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8791724 | 0.70 | KMT2A (0.46) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8791435 | 0.70 | RPS6KB2 (0.30) | — | |
| SCHEMBL8790808 | 0.69 | KDM4E (0.38) | POLBMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35321-E | ANTIDIABETIC AGENT | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| US-5068239-A | Antidiabetic agent | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1991-11-26 | — | — | US | disclosed |