Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930157 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHSD17B10PKM | |
| Hydrochloric Acid SCHEMBL8801734 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHSD17B10PKM | |
| SCHEMBL10941833 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNATSHRESR1 | |
| SCHEMBL8973493 | 0.78 | STS (0.47) | ALDH1A1MAPTLMNATSHRESR1 | |
| SCHEMBL17147852 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNATSHRESR1 | |
| SCHEMBL27516574 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNATSHRESR1 | |
| SCHEMBL16173995 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNATSHRESR1 | |
| Hydrochloric Acid SCHEMBL9148624 | 0.77 | STS (0.46) | ALDH1A1MAPTLMNATSHRESR1 | |
| SCHEMBL102285 | 0.77 | KMT2A (0.54) | ALDH1A1MAPTLMNAHSD17B10PKM | |
| SCHEMBL4786272 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556890-B2 | Heteroaryl compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2020-02-11 | — | — | US | disclosed |
| US-20180118727-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2018-05-03 | — | — | US | disclosed |
| US-5508441-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5430006-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556890-B2 | Heteroaryl compounds and methods of use thereof | COMT, GRIN2C, TPMT | ALDH1A1 1165/4885MAPT 185/4885LMNA 3780/4885 |
| US-20180118727-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | COMT, GRIN2C, TPMT | ALDH1A1 1165/4885MAPT 185/4885LMNA 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.