SCHEMBL102285

SCHEMBL102285

COC(=O)c1sccc1N

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
NPC1 O15118 2/20 0.53
MEN1 O00255 2/20 0.51
CYP1A2 P05177 1/20 0.51
KDM4E B2RXH2 4/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 3/20 0.50
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 2/20 0.50
LMNA P02545 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NPSR1 Q6W5P4 2/20 0.47
MAPK10 P53779 2/20 0.47
HSD17B10 Q99714 2/20 0.46
PKM P14618 1/20 0.46
ATM Q13315 1/20 0.46
MAPK1 P28482 1/20 0.46
CFTR P13569 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11047954 0.98 KMT2A (0.53) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL27982364 0.86 LMNA (0.43) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL8709783 0.86 KMT2A (0.43) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL27998679 0.79 MAPK8 (0.48) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL930157 0.79 ALDH1A1 (0.50) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL8220233 0.79 ALDH1A1 (0.46) KMT2ANPC1MEN1KDM4EMAPT
SCHEMBL27780712 0.78 KMT2A (0.38) KMT2ANPC1MEN1CYP1A2KDM4E
Hydrochloric Acid SCHEMBL8801734 0.78 ALDH1A1 (0.49) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL70575 0.78 KMT2A (0.56) KMT2ANPC1MEN1CYP1A2KDM4E
SCHEMBL375957 0.78 KMT2A (0.56) KMT2ANPC1MEN1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2639 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994098-A Visible light response thienyl azobenzene compound 上海交通大学绍兴新能源与分子工程研究院 2024-11-22 CN claimed
CN-118854272-A Chemical phosphorus palladium plating solution applied to electronic product 深圳市溢诚电子科技有限公司 2024-10-29 CN claimed
CN-115974833-B Preparation method of 3-aminothiophene oxalate 苏州汉德创宏生化科技有限公司 2024-08-02 CN claimed
CN-116347902-A Perovskite solar cell doped with 3-amino-2-methyl thiophene formate and preparation method thereof 嘉兴学院 2023-06-27 CN claimed
CN-115974833-A Preparation method of 3-aminothiophene oxalate 苏州汉德创宏生化科技有限公司 2023-04-18 CN claimed
CN-114524826-A Preparation process of 7-bromo-4-chlorothiophene [3,2-d ] pyrimidine 郑州猫眼农业科技有限公司 2022-05-24 CN claimed
CN-113248399-A O-amino aromatic amide derivative and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2021-08-13 CN claimed
CN-107964090-B Copolymer containing chlorine-substituted thieno [3,4-b ] thiophene unit, preparation method thereof and polymer photovoltaic device 南方科技大学 2020-04-10 CN claimed
CN-104292242-B Pyrantel compound and preparation, as well as preparation method and application of pyrantel compound and preparation 广州必贝特医药技术有限公司 2017-05-17 CN claimed
CN-104292242-A Pyrantel compound and preparation, as well as preparation method and application of pyrantel compound and preparation GUANGZHOU BEBETTER MEDICINE TECHNOLOGY CO LTD 2015-01-21 CN claimed
CN-101909631-B Process for making thienopyrimidine compounds GENENTECH INC 2012-09-12 CN claimed
US-8153823-B2 2-alkenyl-3-aminothiophene derivative and process for producing thereof MITSUI CHEMICALS, INC. (JP) 2012-04-10 US claimed
CN-101967141-A Method for preparing Chk protein kinase antagonist AZD-7762 SYN THESIS SHANGHAI CO LTD 2011-02-09 CN claimed
CN-101909631-A Process for making thienopyrimidine compounds GENENTECH INC 2010-12-08 CN claimed
US-20100292468-A1 PROCESS FOR MAKING THIENOPYRIMIDINE COMPOUNDS GENETECH, INC 2010-11-18 US claimed
EP-2214675-A1 PROCESS FOR MAKING THIENOPYRIMIDINE COMPOUNDS Genentech, Inc. (US) 2010-08-11 EP claimed
WO-2009055730-A1 PROCESS FOR MAKING THIENOPYRIMIDINE COMPOUNDS GENENTECH, INC. (US) 2009-04-30 WO claimed
CN-101410386-A 2-alkenyl-3-aminothiophene derivative and process for producing the same MITSUI CHEMICALS INC (JP) 2009-04-15 CN claimed
US-20090082579-A1 2-ALKENYL-3-AMINOTHIOPHENE DERIVATIVE AND PROCESS FOR PRODUCING THEREOF MITSUI CHEMICALS, INC. (JP) 2009-03-26 US claimed
EP-2011792-A1 2-ALKENYL-3-AMINOTHIOPHENE DERIVATIVE AND METHOD FOR PRODUCING THE SAME Mitsui Chemicals, Inc. (JP) 2009-01-07 EP claimed