Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.65 |
| ▸ | PGR | P06401 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795827 | 1.00 | NR3C1 (0.65) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL5596318 | 1.00 | NR3C1 (0.65) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL9171213 | 1.00 | NR3C1 (0.65) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL6061364 | 1.00 | NR3C1 (0.65) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL3928985 | 0.85 | CYP3A4 (0.52) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL11647954 | 0.84 | CYP3A4 (0.52) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL11798281 | 0.83 | NR3C1 (0.67) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL9168274 | 0.83 | NR3C1 (0.67) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL10860460 | 0.83 | NR3C1 (0.67) | NR3C1PGRCYP3A4OPRK1DRD1 | |
| SCHEMBL28050398 | 0.83 | NR3C1 (0.67) | NR3C1PGRCYP3A4OPRK1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701445-A1 | AGENTS CONTAINING A COMPOUND WITH AN ANTI-ANDROGEN EFFECT AND A COMPOUND WITH A COMPETITIVE, PROGESTERONE-ANTAGONISTIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994027610-A1 | AGENTS CONTAINING A COMPOUND WITH AN ANTI-ANDROGEN EFFECT AND A COMPOUND WITH A COMPETITIVE, PROGESTERONE-ANTAGONISTIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |