Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.52 |
| ▸ | PGR | P06401 | 6/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647954 | 0.89 | CYP3A4 (0.52) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL11325440 | 0.85 | PGR (0.55) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL11795827 | 0.85 | NR3C1 (0.65) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL6061364 | 0.85 | NR3C1 (0.65) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL5596318 | 0.85 | NR3C1 (0.65) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL9171213 | 0.85 | NR3C1 (0.65) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL8973527 | 0.85 | NR3C1 (0.65) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL3930867 | 0.84 | PGR (0.44) | CYP3A4NR3C1PGRDRD1OPRK1 | |
| SCHEMBL3931592 | 0.79 | HIF1A (0.64) | CYP3A4NR3C1PGRHIF1ACYP2C9 | |
| SCHEMBL3931596 | 0.79 | HIF1A (0.64) | CYP3A4NR3C1PGRHIF1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976997-B1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA,10ALPHA-STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | SOLVAY PHARM GMBH (DE) | 2009-04-08 | — | — | EP | claimed |
| US-20070212751-A1 | Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-09-13 | — | — | US | claimed |
| EP-1976997-B1 | PROCESS FOR THE PREPARATION OF 11BETA-HYDR0XY-9BETA,10ALPHA-STEROIDS EMPLOYING AMYCOLATOPSIS MEDITERRANEI CELLS | SOLVAY PHARM GMBH (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20070212751-A1 | Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-09-13 | — | — | US | disclosed |