Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973604 | 1.00 | KDM1A (0.33) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL8973622 | 1.00 | KDM1A (0.33) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL8973610 | 1.00 | KDM1A (0.33) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL8973601 | 1.00 | KDM1A (0.33) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL7723382 | 0.94 | TRPV4 (0.37) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL7723378 | 0.94 | TRPV4 (0.37) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL7739041 | 0.90 | TRPV4 (0.35) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL7739037 | 0.90 | TRPV4 (0.35) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL7739047 | 0.90 | TRPV4 (0.35) | KDM1ATRPV4EGLN2CHEK1AR | |
| SCHEMBL7739045 | 0.90 | TRPV4 (0.35) | KDM1ATRPV4EGLN2CHEK1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588291-B1 | 2-Fluorobenzonitrile derivative | CHISSO CORP (JP) | 1996-03-27 | — | — | EP | claimed |
| US-5370822-A | Liquid crystals | CHISSO CORPORATION (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0588291-A1 | 2-Fluorobenzonitrile derivative | Chisso Corporation (JP) | 1994-03-23 | — | — | EP | claimed |
| EP-0588291-B1 | 2-Fluorobenzonitrile derivative | CHISSO CORP (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5370822-A | Liquid crystals | CHISSO CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0588291-A1 | 2-Fluorobenzonitrile derivative | Chisso Corporation (JP) | 1994-03-23 | — | — | EP | disclosed |