SCHEMBL8973643

SCHEMBL8973643

C=C(CN(C)CCCC)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.57
MAOB P27338 3/20 0.57
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
EGFR P00533 2/20 0.41
SIGMAR1 Q99720 1/20 0.40
PTGS2 P35354 1/20 0.40
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415451 0.84 MAOA (0.46) MAOAMAOBKMT2AMEN1PTGS2
SCHEMBL10629899 0.82 MAOA (0.64) MAOAMAOBKMT2AMEN1EGFR
SCHEMBL22009538 0.79 MAOA (0.48) MAOAMAOBSIGMAR1
SCHEMBL9223831 0.78 KCNH2 (0.49) MAOAMAOB
SCHEMBL9603181 0.78 KCNH2 (0.49) MAOAMAOB
SCHEMBL9779276 0.78 KCNH2 (0.49) MAOAMAOB
SCHEMBL9779440 0.78 KCNH2 (0.49) MAOAMAOB
SCHEMBL4691160 0.77 MAOA (0.53) MAOAMAOBEGFR
SCHEMBL3449205 0.76 ICMT (0.47) KMT2AMEN1PTGS2
SCHEMBL187719 0.75 EGFR (0.60) MAOAMAOBKMT2AMEN1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439072-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1996-04-03 EP disclosed
EP-0389928-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1995-08-02 EP disclosed
EP-0432727-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1995-07-05 EP disclosed
EP-0307227-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1995-06-28 EP disclosed
US-5227272-A Layer containing inorganic photoconductor and binder resin with block copolymer composed of acidic component and hydrocarbyl methacrylate component FUJI PHOTO FILM CO., LTD. (JP) 1993-07-13 US disclosed
US-5183721-A Photoconductive particles and binder resin FUJI PHOTO FILM CO., LTD. (JP) 1993-02-02 US disclosed
US-5147752-A Crosslinked binder FUJI PHOTO FILM CO., LTD. (JP) 1992-09-15 US disclosed
US-5089368-A Binder resin of graft copolymer made from an acid group-containing macromolecular block polymer monomer FUJI PHOTO FILM CO., LTD. (JP) 1992-02-18 US disclosed
US-5063130-A Photoconductive layer containing inorganic particles and a binder comprising an acrylic copolymer having a polyester macromonomer; electrostatics; moisture resistance; durability FUJI PHOTO FILM CO., LTD. (JP) 1991-11-05 US disclosed
EP-0439072-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-31 EP disclosed
EP-0432727-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
US-4968572-A EXCELLENT ELECTROSTATIC CHARACTERISTICS AND IMAGE FORMATION PERFORMANCE IN SPITE OF HEAT AND HUMIDITY FUJI PHOTO FILM CO., LTD. (JP) 1990-11-06 US disclosed
EP-0389928-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-03 EP disclosed