SCHEMBL8973652

SCHEMBL8973652

CC(C(N)=O)=C(C(C)N(C)C)C(C)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2713252 0.74 LMNA (0.39) TDP1LMNAALOX15BLMPMP22
SCHEMBL3951408 0.72 TP53 (0.38) TDP1LMNAALOX15BLMPMP22
SCHEMBL8974696 0.71 TDP1 (0.32) TDP1
SCHEMBL629813 0.71
SCHEMBL1191180 0.71
SCHEMBL774011 0.71
Hydrochloric Acid SCHEMBL6631500 0.69
Hydrochloric Acid SCHEMBL31606745 0.69
Hydrochloric Acid SCHEMBL22346326 0.69 CHRNB2 (0.37) CHRNB2CHRNB4CHRNA3CHRNA4TDP1
Hydrochloric Acid SCHEMBL22346327 0.69 CHRNB2 (0.37) CHRNB2CHRNB4CHRNA3CHRNA4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604109-B1 Suspension polymerization process for water-soluble monomers ROHM & HAAS (US) 1996-10-02 EP claimed
US-5498678-A Suspension polymerization process for water-soluble monomers ROHM AND HAAS COMPANY (US) 1996-03-12 US claimed
EP-0604109-A2 Suspension polymerization process for water-soluble monomers ROHM AND HAAS COMPANY (US) 1994-06-29 EP claimed
CN-115003715-A Method for preparing silicone-acrylate hybrid compositions and hybrid compositions formed thereby 美国陶氏有机硅公司 2022-09-02 CN disclosed
EP-2859021-A1 MIXED SALT SUSPENSION POLYMERIZATION PROCESS AND RESINS AND CATALYSTS PRODUCED THEREOF Rohm and Haas Company (US) 2015-04-15 EP disclosed
WO-2013188221-A1 MIXED SALT SUSPENSION POLYMERIZATION PROCESS AND RESINS AND CATALYSTS PRODUCED THEREOF ROHM AND HAAS COMPANY (US) 2013-12-19 WO disclosed
EP-0604109-B1 Suspension polymerization process for water-soluble monomers ROHM & HAAS (US) 1996-10-02 EP disclosed
US-5498678-A Suspension polymerization process for water-soluble monomers ROHM AND HAAS COMPANY (US) 1996-03-12 US disclosed