Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973919 | 0.78 | KCNH2 (0.35) | KIF11APPKCNH2PDE10AKCNN4 | |
| SCHEMBL9262619 | 0.78 | ITGB3 (0.40) | NR3C2 | |
| SCHEMBL19514887 | 0.76 | APP (0.55) | HRH1APPKCNH2PDE10ANR3C2 | |
| SCHEMBL30336032 | 0.76 | APP (0.55) | HRH1APPKCNH2PDE10ANR3C2 | |
| SCHEMBL522831 | 0.74 | KCNH2 (0.56) | HRH1KCNH2MAOA | |
| SCHEMBL8973859 | 0.72 | HTT (0.51) | — | |
| SCHEMBL8973863 | 0.72 | KMT2A (0.37) | KIF11 | |
| SCHEMBL19101913 | 0.70 | APP (0.74) | HRH1APPKCNH2CYP2C19IRAK4 | |
| SCHEMBL8973878 | 0.68 | PDE5A (0.40) | KCNH2NR3C2 | |
| SCHEMBL4718869 | 0.68 | NOS1 (0.46) | HRH1APPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5548077-A | REACTING WITH CARBOHYDRATE COMPOUND TO FORM SCHIFF BASE, REDUCING SCHIFF BASE | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-08-20 | — | — | US | disclosed |