Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TXN | P10599 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837292 | 0.85 | NFKB1 (0.78) | NFKB1SMN1; SMN2MAPK1MAPTTXN | |
| SCHEMBL6536659 | 0.80 | NPC1 (0.72) | NFKB1SMN1; SMN2MAPK1MAPTTXN | |
| SCHEMBL3500246 | 0.79 | NFKB1 (0.69) | NFKB1SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL21004551 | 0.79 | NFKB1 (0.66) | NFKB1SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL14071639 | 0.78 | NFKB1 (0.63) | NFKB1SMN1; SMN2MAPK1MAPTTXN | |
| SCHEMBL29950147 | 0.76 | NFKB1 (0.59) | NFKB1SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL3958499 | 0.76 | NFKB1 (0.59) | NFKB1SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL23643402 | 0.76 | NFKB1 (0.92) | NFKB1SMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL1391141 | 0.76 | NFKB1 (0.64) | NFKB1SMN1; SMN2MAPK1MAPTTXN | |
| SCHEMBL8972835 | 0.76 | NFKB1 (0.64) | NFKB1SMN1; SMN2MAPK1MAPTTXN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | claimed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | claimed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | claimed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | claimed |