SCHEMBL8974000

SCHEMBL8974000

Cc1ccc2[nH]c(CCc3ccccc3)nc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.67
NPC1 O15118 3/20 0.67
KMT2A Q03164 3/20 0.58
POLB P06746 1/20 0.58
MAPT P10636 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
ALDH1A1 P00352 1/20 0.57
MEN1 O00255 1/20 0.57
GFER P55789 1/20 0.57
NTRK1 P04629 5/20 0.53
GAA P10253 1/20 0.51
NTRK2 Q16620 2/20 0.51
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
HDAC6 Q9UBN7 1/20 0.49
PDE10A Q9Y233 1/20 0.48
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47
TUBA1B P68363 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2952408 0.91 KMT2A (0.61) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8974011 0.91 KMT2A (0.57) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8974007 0.91 KMT2A (0.63) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8974004 0.88 KMT2A (0.77) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8973995 0.88 GAA (0.68) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8973973 0.84 RAB9A (0.65) RAB9ANPC1KMT2AMAPTSMN1; SMN2
SCHEMBL6373674 0.83 RAB9A (0.64) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8974006 0.82 KMT2A (0.55) RAB9ANPC1KMT2APOLBSMN1; SMN2
SCHEMBL3764806 0.82 MAPT (0.78) RAB9ANPC1KMT2APOLBMAPT
SCHEMBL8957996 0.81 NPC1 (0.76) RAB9ANPC1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551112-B1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO LTD (JP) 1996-04-03 EP disclosed
US-5476947-A Excellent rust preventing effect, useful as corrosion resistance protective coating in printed wiring boards MEC CO., LTD. (JP) 1995-12-19 US disclosed
US-5435860-A Corrosion resistance for printed circuits MEC CO., LTD. (JP) 1995-07-25 US disclosed
EP-0551112-A1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO., Ltd. (JP) 1993-07-14 EP disclosed