SCHEMBL8973995

SCHEMBL8973995

Cc1ccc2[nH]c(Cc3ccccc3)nc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.68
PKM P14618 2/20 0.57
TSHR P16473 1/20 0.57
MAPT P10636 2/20 0.56
KDM4E B2RXH2 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
POLB P06746 3/20 0.55
EGFR P00533 2/20 0.55
ERBB2 P04626 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
GRIN1 Q05586 2/20 0.52
GRIN2B Q13224 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974000 0.88 RAB9A (0.67) GAAMAPTPOLBNPC1RAB9A
SCHEMBL8973998 0.87 POLB (0.71) GAAPKMTSHRMAPTKDM4E
SCHEMBL2952408 0.85 KMT2A (0.61) GAAMAPTPOLBNPC1RAB9A
SCHEMBL8974011 0.85 KMT2A (0.57) GAAMAPTPOLBNPC1RAB9A
SCHEMBL28642276 0.84 POLB (0.56) GAAMAPTTDP1POLBEGFR
SCHEMBL20723555 0.84 POLB (0.76) GAAPKMTSHRMAPTKDM4E
SCHEMBL8974435 0.84 GAA (0.64) GAAPKMTSHRMAPTKDM4E
SCHEMBL4164834 0.83 GAA (0.66) GAAPKMTSHRMAPTKDM4E
SCHEMBL19884911 0.83 GAA (0.66) GAAPKMTSHRMAPTKDM4E
SCHEMBL5081088 0.83 GAA (0.66) GAAPKMTSHRMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206372-B New application of N-cyano-N-phenyl aryl sulfonamide and method for N-aryl sulfonylation of 2-substituted benzimidazole 长沙理工大学 2021-07-27 CN disclosed
EP-0551112-B1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO LTD (JP) 1996-04-03 EP disclosed
US-5476947-A Excellent rust preventing effect, useful as corrosion resistance protective coating in printed wiring boards MEC CO., LTD. (JP) 1995-12-19 US disclosed
US-5435860-A Corrosion resistance for printed circuits MEC CO., LTD. (JP) 1995-07-25 US disclosed
EP-0551112-A1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO., Ltd. (JP) 1993-07-14 EP disclosed