SCHEMBL8974015

SCHEMBL8974015

Cc1ccc2[nH]c(CCc3cccc(C)c3C)nc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
POLB P06746 1/20 0.52
MEN1 O00255 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
GFER P55789 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
THRB P10828 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PDE10A Q9Y233 3/20 0.41
NTRK1 P04629 2/20 0.40
PSMD14 O00487 1/20 0.40
MMP2 P08253 1/20 0.40
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NTRK2 Q16620 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974019 0.89 KMT2A (0.68) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL8974006 0.89 KMT2A (0.55) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL8974018 0.83 KMT2A (0.58) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL8974237 0.81 KMT2A (0.58) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL8974008 0.78 KMT2A (0.72) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL8974000 0.77 RAB9A (0.67) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL8974007 0.77 KMT2A (0.63) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL6757230 0.76 KMT2A (0.60) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL4594659 0.75 KMT2A (0.58) KMT2APOLBMEN1NPC1RAB9A
SCHEMBL9598927 0.75 KMT2A (0.58) KMT2APOLBMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551112-B1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO LTD (JP) 1996-04-03 EP disclosed
US-5476947-A Excellent rust preventing effect, useful as corrosion resistance protective coating in printed wiring boards MEC CO., LTD. (JP) 1995-12-19 US disclosed
US-5435860-A Corrosion resistance for printed circuits MEC CO., LTD. (JP) 1995-07-25 US disclosed
EP-0551112-A1 Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same MEC CO., Ltd. (JP) 1993-07-14 EP disclosed