Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbenicillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | RECQL | P46063 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | TEK | Q02763 | 1/20 | 0.65 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | FPR1 | P21462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbenicillin SCHEMBL11317057 | 0.94 | LMNA (0.88) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL54797 | 0.94 | LMNA (1.00) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL11311430 | 0.94 | LMNA (1.00) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL11317053 | 0.94 | LMNA (0.88) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL10811380 | 0.94 | LMNA (0.88) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL193748 | 0.92 | LMNA (0.85) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL11310979 | 0.91 | PTGS1 (0.77) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL11604897 | 0.91 | PTGS1 (0.77) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL11310973 | 0.91 | PTGS1 (0.77) | LMNAKDM4ERECQLTDP1HSD17B10 | |
| Carbenicillin SCHEMBL320405 | 0.91 | PTGS1 (0.77) | LMNAKDM4ERECQLTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567599-A | INTRODUCING EXOGENOUS DNA FRAGMENT INTO PLANT USING AGROBACTERIUM AS VECTOR | FLORIGENE EUROPE B.V. (NL) | 1996-10-22 | — | — | US | disclosed |
| EP-0536327-A4 | — | — | 1994-02-16 | — | — | EP | disclosed |
| EP-0536327-A1 | ROSE PLANTS AND METHODS FOR THEIR PRODUCTION AND GENETIC TRANSFORMATION | FLORIGENE EUROPE B.V. (NL) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992003041-A1 | METHOD FOR PRODUCING TRANSFORMED CHRYSANTHEMUM PLANTS | FLORIGENE BV (NL) | 1992-03-05 | — | — | WO | disclosed |
| WO-1992000371-A1 | ROSE PLANTS AND METHODS FOR THEIR PRODUCTION AND GENETIC TRANSFORMATION | DNA PLANT TECHNOLOGY CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |