Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459950 | 0.76 | ALDH1A1 (0.36) | SMN1; SMN2CRBNALDH1A1LMNACYP3A4 | |
| SCHEMBL11931948 | 0.76 | ALDH1A1 (0.36) | SMN1; SMN2CRBNALDH1A1LMNACYP3A4 | |
| SCHEMBL17381142 | 0.76 | ALDH1A1 (0.36) | SMN1; SMN2CRBNALDH1A1LMNACYP3A4 | |
| SCHEMBL10355531 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2CA1CA9 | |
| SCHEMBL5708446 | 0.71 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8609740 | 0.71 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13697409 | 0.68 | SMN1; SMN2 (0.37) | SMN1; SMN2CRBNALDH1A1LMNACYP3A4 | |
| SCHEMBL13697404 | 0.68 | SMN1; SMN2 (0.37) | SMN1; SMN2CRBNALDH1A1LMNACYP3A4 | |
| SCHEMBL10431444 | 0.68 | SMN1; SMN2 (0.37) | SMN1; SMN2CRBNALDH1A1LMNACYP3A4 | |
| SCHEMBL3137615 | 0.67 | ALDH1A1 (0.31) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577449-B1 | Tris-(acetoacetoxy-2-ethyl)-amine and its water soluble salts, process for their preparation, use as formaldehyde scavengers and process for the finishing of textiles | HOECHST FRANCE (FR) | 1996-03-13 | — | — | EP | claimed |
| JP-6065167-A | — | — | None | — | — | JP | disclosed |
| EP-3783048-B1 | A METHOD FOR APPLYING A FOAM COMPOSITION USING SPRAY FOAM EQUIPMENT | HOLCIM TECHNOLOGY LTD (CH) | 2023-05-10 | — | — | EP | disclosed |
| US-20230097878-A1 | FOAM COMPOSITIONS | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2023-03-30 | — | — | US | disclosed |
| US-11525029-B2 | Foam compositions | HOLCIM TECHNOLOGY LTD (CH) | 2022-12-13 | — | — | US | disclosed |
| EP-3783048-A1 | A METHOD FOR APPLYING A FOAM COMPOSITION USING SPRAY FOAM EQUIPMENT | Firestone Building Products Company, LLC (US) | 2021-02-24 | — | — | EP | disclosed |
| CN-112159358-A | Preparation method of oxalagogri intermediate | 上海朴颐化学科技有限公司 | 2021-01-01 | — | — | CN | disclosed |
| US-20200299456-A1 | FOAM COMPOSITIONS | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2020-09-24 | — | — | US | disclosed |
| EP-3154929-B1 | METHOD OF PREPARING A FOAM | FIRESTONE BUILDING PROD CO LLC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10696784-B2 | Foam compositions | FIRESTONE BUILDING PRODUCTS COMPANY, LLC (US) | 2020-06-30 | — | — | US | disclosed |
| US-5332785-A | Liquid coating composition comprising acetoacetate modified epoxy resin and blocked polyamine | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| JP-H0665167-A | TRIS(2-ACETOACETOXY ETHYL)-AMINE, ITS HYDROSOLUBLE SALT, ITS PREPARATION, USE THEREOF AS FORMALDEHYDE COLLECTOR AND FINISHING PROCESS FOR FABRIC | SOC FR HOECHST | 1994-03-08 | — | — | JP | disclosed |
| EP-0564883-A1 | Liquid coating composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | disclosed |
| US-4271187-A | Substituted phenyl alanine antihypertensive agents | MERCK & CO., INC. (US) | 1981-06-02 | — | — | US | disclosed |
| US-4206216-A | Antihypertensive N-heterocyclicalanines | MERCK & CO., INC. (US) | 1980-06-03 | — | — | US | disclosed |
| US-4170654-A | Antihypertensive compositions containing N-heterocyclicalanines and α- | MERCK & CO., INC. (US) | 1979-10-09 | — | — | US | disclosed |
| US-4160835-A | Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid | MERCK & CO., INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4156734-A | Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid | MERCK & CO., INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4153715-A | Indolyl amino acids useful as antihypertensive agents | MERCK & CO., INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4065572-A | Amino acids and esters thereof useful as antihypertensive agents | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | disclosed |