Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708446 | 1.00 | ALDH1A1 (0.34) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29265283 | 0.80 | SMN1; SMN2 (0.37) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7053769 | 0.74 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL8974251 | 0.71 | SMN1; SMN2 (0.42) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30812624 | 0.68 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL10355531 | 0.67 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL11135928 | 0.64 | — | — | |
| SCHEMBL7992810 | 0.62 | LMNA (0.40) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3954537 | 0.62 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL14159710 | 0.61 | TSHR (0.43) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528527-B1 | Conjugates | ZENECA LTD (GB) | 1998-04-08 | — | — | EP | disclosed |
| EP-0528527-A2 | Conjugates | ZENECA LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |