SCHEMBL8974278

SCHEMBL8974278

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(=O)(O)O[C@@H](C(=O)O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.42
PDE4A P27815 1/20 0.36
PGD P52209 1/20 0.36
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
LMNA P02545 1/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3711551 0.90 PGD (0.42) MPIPDE4APGDPGK1PGK2
SCHEMBL7745225 0.88 MPI (0.41) MPIPGD
SCHEMBL15874622 0.85 MPI (0.45) MPILMNA
SCHEMBL3487364 0.85 MPI (0.45) MPILMNA
SCHEMBL2883546 0.85 MPI (0.45) MPILMNA
SCHEMBL5921670 0.85 MPI (0.45) MPILMNA
SCHEMBL8588218 0.80 MPI (0.38) MPIPDE4APGDLMNA
Mannose 6-Phosphate SCHEMBL28382827 0.80 PGD (0.54) MPIPDE4APGDUSP2SLCO1B1
Mannose 6-Phosphate SCHEMBL6054950 0.80 MPI (0.66) MPIPGDLMNAPGK1PGK2
Mannose 6-Phosphate SCHEMBL6245545 0.80 MPI (0.66) MPIPGDLMNAPGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704053-A1 ANALYSIS OF ANALYTES IN BIOLOGICAL FLUIDS BECKMAN INSTRUMENTS, INC. (US) 1996-04-03 EP disclosed
WO-1995028637-A1 ANALYSIS OF ANALYTES IN BIOLOGICAL FLUIDS BECKMAN INSTRUMENTS, INC. (US) 1995-10-26 WO disclosed