Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117936 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1RORC | |
| SCHEMBL8973810 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8974391 | 0.86 | PTGS2 (0.59) | PTGS2PTGS1RORC | |
| SCHEMBL9117072 | 0.84 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL8974089 | 0.83 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8974669 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1RORC | |
| SCHEMBL8974128 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1RORC | |
| SCHEMBL8974331 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL9115937 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1RORC | |
| SCHEMBL8973837 | 0.77 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576339-A | Pyridyl substituted cyclopentadienes for the treatment of inflamation | HUANG HORNG-CHIH (US) | 1996-11-19 | — | — | US | disclosed |
| US-5418254-A | Side effect reduction | G. D. SEARLE & CO. (US) | 1995-05-23 | — | — | US | disclosed |