Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974365 | 1.00 | ALOX5 (0.39) | ALOX5CYP3A4CYP2C9ERN1PTGES | |
| SCHEMBL9655150 | 0.93 | CYP3A4 (0.41) | ALOX5CYP3A4CYP2C9ERN1MEN1 | |
| SCHEMBL9652510 | 0.93 | CYP3A4 (0.41) | ALOX5CYP3A4CYP2C9ERN1MEN1 | |
| SCHEMBL9655265 | 0.90 | PSEN1 (0.37) | ALOX5ERN1PTGESPPARG | |
| SCHEMBL8974534 | 0.90 | PSEN1 (0.37) | ALOX5ERN1PTGESPPARG | |
| SCHEMBL8974675 | 0.90 | PSEN1 (0.37) | ALOX5ERN1PTGESPPARG | |
| SCHEMBL8974350 | 0.84 | ALOX5 (0.37) | ALOX5ERN1MEN1KMT2A | |
| SCHEMBL8974836 | 0.84 | ALOX5 (0.37) | ALOX5ERN1MEN1KMT2A | |
| SCHEMBL8974364 | 0.84 | ALOX5 (0.37) | ALOX5ERN1MEN1KMT2A | |
| SCHEMBL9655192 | 0.82 | PSEN1 (0.36) | ALOX5ERN1PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527948-A | SUBSTITUTED NAPHTHYL-ALKENOIC ACIDS FOR TREATING AUTOIMMUNE DISORDERS | EISAI CORP. LTD. (JP) | 1996-06-18 | — | — | US | disclosed |