Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652510 | 1.00 | CYP3A4 (0.41) | CYP3A4CYP2C9ALOX5MEN1KMT2A | |
| SCHEMBL8974367 | 0.93 | ALOX5 (0.39) | CYP3A4CYP2C9ALOX5MEN1KMT2A | |
| SCHEMBL8974365 | 0.93 | ALOX5 (0.39) | CYP3A4CYP2C9ALOX5MEN1KMT2A | |
| SCHEMBL9652527 | 0.89 | PSEN1 (0.36) | ALOX5MEN1KMT2AERN1ATM | |
| SCHEMBL9655192 | 0.89 | PSEN1 (0.36) | ALOX5MEN1KMT2AERN1ATM | |
| SCHEMBL9652523 | 0.89 | PSEN1 (0.36) | ALOX5MEN1KMT2AERN1ATM | |
| SCHEMBL9652529 | 0.84 | KMT2A (0.45) | CYP3A4CYP2C9MEN1KMT2AERN1 | |
| SCHEMBL9652534 | 0.84 | KMT2A (0.45) | CYP3A4CYP2C9MEN1KMT2AERN1 | |
| SCHEMBL8974825 | 0.83 | ERN1 (0.37) | ALOX5MEN1KMT2AERN1ATM | |
| SCHEMBL8973822 | 0.83 | ERN1 (0.37) | ALOX5MEN1KMT2AERN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134111-A | Inhibitors of interleukin-1 as antiinflammatory agents | EISAI CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |