Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165010 | 0.78 | DPP4 (0.44) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL28363604 | 0.74 | DPP4 (0.50) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL946139 | 0.74 | DPP4 (0.50) | DPP4F2ADRA2AADRA2CLMNA | |
| Phenylglycine SCHEMBL30559595 | 0.74 | CYP2D6 (0.56) | DPP4F2LMNAKDM4EALDH1A1 | |
| SCHEMBL12729962 | 0.74 | DPP4 (0.50) | DPP4F2ADRA2AADRA2CLMNA | |
| Phenylglycine SCHEMBL157180 | 0.74 | CYP2D6 (0.56) | DPP4F2LMNAKDM4EALDH1A1 | |
| Phenylglycine SCHEMBL11576917 | 0.74 | CYP2D6 (0.56) | DPP4F2LMNAKDM4EALDH1A1 | |
| Phenylglycine SCHEMBL159420 | 0.74 | CYP2D6 (0.56) | DPP4F2LMNAKDM4EALDH1A1 | |
| Phenylglycine SCHEMBL31402004 | 0.74 | CYP2D6 (0.56) | DPP4F2LMNAKDM4EALDH1A1 | |
| SCHEMBL8643386 | 0.74 | DPP4 (0.50) | DPP4F2ADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60248663-A | — | — | None | — | — | JP | disclosed |
| JP-6220016-A | — | — | None | — | — | JP | disclosed |
| EP-2986625-B1 | MIXED MODE LIGANDS | BIO RAD LABORATORIES (US) | 2020-03-11 | — | — | EP | disclosed |
| US-10583429-B2 | Mixed mode ligands | BIO-RAD LABORATORIES, INC. (US) | 2020-03-10 | — | — | US | disclosed |
| CN-105579463-B | Mixed mode ligands | 生物辐射实验室股份有限公司 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018106519-A1 | HETEROCYCLIC COMPOUNDS AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-06-14 | — | — | WO | disclosed |
| US-9556469-B2 | Method for classifying the presence or absence of a microorganism in a biological medium | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-01-31 | — | — | US | disclosed |
| CN-105579463-A | Mixed mode ligands | BIO RAD LABORATORIES INC | 2016-05-11 | — | — | CN | disclosed |
| EP-2986625-A2 | MIXED MODE LIGANDS | Bio-rad Laboratories, Inc. (US) | 2016-02-24 | — | — | EP | disclosed |
| US-20150258539-A1 | MIXED MODE LIGANDS | BIO RAD LABORATORIES (US) | 2015-09-17 | — | — | US | disclosed |
| JP-H06220016-A | SUBSTITUTED PHENYLTHIOACETIC ACID | SUMITOMO CHEM CO LTD | 1994-08-09 | — | — | JP | disclosed |
| US-5237070-A | Antiallergens, inhibiting bronchoconstriction | RIKER LABORATORIES, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0212848-B1 | SUBSTITUTED-DI-T-BUTYLPHENOLS | RIKER LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| US-4801408-A | 3-AMINO-4-FLUORO-6-HALOPHENYLTHIOACETIC ACIDS, 5-SUBSTITUTED ACETANILIDES, HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0126419-B1 | 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4709049-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| US-4684397-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0212848-A2 | Substituted-di-t-butylphenols | RIKER LABORATORIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |
| JP-S60248663-A | AMINOPHENYLTHIOACETIC ACID COMPOUND AND ITS PREPARATION | SUMITOMO CHEM CO LTD | 1985-12-09 | — | — | JP | disclosed |
| EP-0126419-A1 | 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150258539-A1 | MIXED MODE LIGANDS | MRPL21, FABP2, MYOF | DPP4 2961/4885F2 2752/4885ADRA2A 4395/4885 |
| US-10583429-B2 | Mixed mode ligands | MRPL21, CD2BP2, FABP1 | DPP4 3433/4885F2 1642/4885ADRA2A 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.