SCHEMBL8974450

SCHEMBL8974450

CCC(C)(C)[N]c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 4/20 0.39
NOS1 P29475 4/20 0.39
NOS2 P35228 2/20 0.39
ALDH1A1 P00352 2/20 0.38
HTR3E A5X5Y0 1/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
HTR3B O95264 1/20 0.36
PLAU P00749 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
TP53 P04637 1/20 0.35
PSIP1 O75475 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
MAPT P10636 1/20 0.33
SLC6A2 P23975 1/20 0.33
RIPK1 Q13546 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50033 0.74 ALDH1A1 (0.45) NOS3NOS1ALDH1A1HTR3ESLC22A2
SCHEMBL8586685 0.68 MAPK1 (0.42) NOS3NOS1ALDH1A1TAAR1MAPT
SCHEMBL53706 0.64
SCHEMBL6986783 0.64 ALDH1A1 (0.45) NOS3NOS1ALDH1A1HTR3ESLC22A2
SCHEMBL3607297 0.64 ALDH1A1 (0.45) NOS3NOS1ALDH1A1HTR3ESLC22A2
Azobenzene SCHEMBL15261802 0.64 ALDH1A1 (0.71) ALDH1A1MAPTMEN1KMT2A
SCHEMBL474982 0.64 TAAR1 (0.50) ALDH1A1TP53TAAR1MAPTKMT2A
SCHEMBL149490 0.63 ALDH1A1 (0.39) NOS3NOS1NOS2ALDH1A1HTR3E
SCHEMBL879532 0.63 TAAR1 (0.44) ALDH1A1TP53TAAR1MAPTKMT2A
SCHEMBL14608023 0.63 TAAR1 (0.44) ALDH1A1TP53TAAR1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597287-B1 Process for the preparation of anthraquinones BASF AG (DE) 1996-04-10 EP disclosed
US-5387704-A Preparation of anthraquinones BASF AKTIENGESELLSCHAFT (DE) 1995-02-07 US disclosed
EP-0597287-A1 Process for the preparation of anthraquinones BASF Aktiengesellschaft (DE) 1994-05-18 EP disclosed