Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974489 | 0.72 | ABCB1 (0.35) | — | |
| SCHEMBL8974503 | 0.72 | ABCB1 (0.37) | MAOA | |
| SCHEMBL12228067 | 0.70 | CD44 (0.37) | — | |
| SCHEMBL12228068 | 0.68 | APLNR (0.36) | MAOA | |
| SCHEMBL8974210 | 0.68 | PTPN1 (0.32) | — | |
| SCHEMBL8974383 | 0.67 | BACE1 (0.33) | — | |
| SCHEMBL20700286 | 0.66 | BACE1 (0.34) | — | |
| SCHEMBL20558194 | 0.65 | BACE1 (0.38) | — | |
| SCHEMBL4680048 | 0.65 | BACE1 (0.40) | — | |
| SCHEMBL14881515 | 0.65 | HTR2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527948-A | SUBSTITUTED NAPHTHYL-ALKENOIC ACIDS FOR TREATING AUTOIMMUNE DISORDERS | EISAI CORP. LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5298649-A | Antiinflammatory agents, rheumatic agents and treatment of autoimmune diseases | EISAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5134111-A | Inhibitors of interleukin-1 as antiinflammatory agents | EISAI CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |