Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408400 | 1.00 | MEN1 (0.64) | MEN1KMT2APOLBCTDSP1MMP9 | |
| SCHEMBL28429475 | 0.90 | MEN1 (0.54) | MEN1KMT2APOLBCTDSP1MMP9 | |
| SCHEMBL197182 | 0.86 | KEAP1 (0.58) | MEN1KMT2APOLBCTDSP1KEAP1 | |
| SCHEMBL197183 | 0.86 | KEAP1 (0.58) | MEN1KMT2APOLBCTDSP1KEAP1 | |
| SCHEMBL7551261 | 0.86 | MEN1 (0.66) | MEN1KMT2APOLBCTDSP1MMP9 | |
| SCHEMBL7551272 | 0.86 | MEN1 (0.66) | MEN1KMT2APOLBCTDSP1MMP9 | |
| SCHEMBL28002396 | 0.85 | ALDH1A1 (0.58) | MEN1KMT2AKEAP1NFE2L2LMNA | |
| SCHEMBL8310909 | 0.84 | MEN1 (0.68) | MEN1KMT2APOLBCTDSP1MMP9 | |
| SCHEMBL7855088 | 0.84 | MEN1 (0.68) | MEN1KMT2APOLBCTDSP1MMP9 | |
| SCHEMBL8313972 | 0.84 | MEN1 (0.68) | MEN1KMT2APOLBCTDSP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703899-A1 | ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029267-A1 | ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1994-12-22 | — | — | WO | disclosed |